In many cases, after making the change, all you need to do is click the "Finished" button on the Finished tab in the Production Wizard.
After editing an activity from the Production Wizard, in addition to clicking the "Save" and/or "Next" button for the tab you made the change on, you must be sure to also click the "Finished" button on the finished tab.
If that does not work, you may need to "Save" after making the change, then click "Next" button. Always be sure to click the "Finished" button on the finished tab as well.